Vein wrapping promotes M2 macrophage polarization in a rat chronic constriction injury model
نویسندگان
چکیده
منابع مشابه
Microinjection of calcitonin in midbrain periaqueductal gray attenuates hyperalgesia in a chronic constriction injury rat model
Objective(s): As heat, pain is one of the most common clinical symptoms. Generally, calcitonin (CT) is prescribed as an analgesic agent for the treatment of pain, especially for the pain caused by osteoporosis or primary and metastatic bone tumor. However, the detailed mechanism remains unknown.Materials and Methods: In this study, chronic constriction injury (CCI) rat model was created, and ho...
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Neuropathic pain treatment remains a challenge because pathomechanism is not fully understood. It is believed that glial activation and increased spinal nociceptive factors are crucial for neuropathy. We investigated the effect of parthenolide (PTL) on the chronic constriction injury to the sciatic nerve (CCI)-induced neuropathy in rat. We analyzed spinal changes in glial markers and M1 and M2 ...
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ژورنال
عنوان ژورنال: Journal of Orthopaedic Research®
سال: 2018
ISSN: 0736-0266
DOI: 10.1002/jor.23875